2019
Kishida N, Maki T, Takagi Y, Yasuda K, Kinoshita H, Ayaki T, Noro T, Kinoshita Y, Ono Y, Kataoka H, Yoshida K, Lo EH, Arai K, Miyamoto S, Takahashi R. Role of Perivascular Oligodendrocyte Precursor Cells in Angiogenesis After Brain Ischemia. J Am Heart Assoc. May 7;8(9)(2019)
Motoi S,Toyoda H,Obara T,Ohta E,Arita Y,Negishi K,Moriya K,Kuboi Y,Soejima M,Imai T,Ido A,Tsubouchi H,Kawano T. Anti-Apoptotic Effects of Recombinant Human Hepatocyte Growth Factor on Hepatocytes Were Associated with Intrahepatic Hemorrhage Suppression Indicated by the Preservation of Prothrombin Time. Int J Mol Sci. Apr 12;20(8)(2019)
Hoshino-Negishi K, Ohkuro M, Nakatani T, Kuboi Y, Nishimura M, Ida Y, Kakuta J, Hamaguchi A, Kumai M, Kamisako T, Sugiyama F, Ikeda W, Ishii N, Yasuda N, Imai T. Role of Anti-Fractalkine Antibody in Suppression of Joint Destruction by Inhibiting Migration of Osteoclast Precursors to the Synovium in Experimental Arthritis. Arthritis & Rheumatology. Feb;71(2):222-231.(2019)
Morita N, Umemoto E, Fujita S, Hayashi A, Kikuta J, Kimura I, Haneda T, Imai T, Inoue A, Mimuro H, Maeda Y, Kayama H, Okumura R, Aoki J, Okada N, Kida T, Ishii M, Nabeshima R, Takeda K. GPR31-dependent dendrite protrusion of intestinal CX3CR1+ cells by bacterial metabolites. Nature. Feb;566(7742):110-114.(2019)
2018
Ikeda W, Nakatani T, Uemura A. Cataract-preventing contact lens for in vivo imaging of mouse retina. BioTechniques. Aug 9;65(2)(2018)
Sasaki A, Nagatake T, Egami R, Takigawa I, Ikeda W, Nakatani T, Kunisawa J, Fujita Y. Obesity Suppresses Cell-Competition-Mediated Apical Elimination of RasV12-Transformed Cells from Epithelial Tissues. Cell Rep. Apr 24;23(4):974-982.(2018)
Tanaka Y, Takeuchi T, Umehara H, Nanki T, Yasuda N, Tago F, Kawakubo M, Kitahara Y, Hojo S, Kawano T, Imai T. Safety, pharmacokinetics, and efficacy of E6011, an antifractalkine monoclonal antibody, in a first-in-patient phase 1/2 study on rheumatoid arthritis. Mod Rheumatol. Jan;28(1):58-65.(2018)
2017
Vibulyaseck S, Fujita H, Luo Y, Tran AK, Oh-Nishi A, Ono Y, Hirano S, Sugihara I. Spatial rearrangement of Purkinje cell subsets forms the transverse and longitudinal compartmentalization in the mouse embryonic cerebellum. J Comp Neurol. Oct 1;525(14):2971-2990.(2017)
Sasai K, Takao-Rikitsu E, Sukezane T, Yanagita E, Nakagawa H, Itoh-Yagi M, Izumi Y, Itoh T, Akagi T. Engineering cancer stem-like cells from normal human lung epithelial cells. PLoS One. Apr 5;12(4)(2017)
Ogura S, Kurata K, Hattori Y, Takase H, Ishiguro-Oonuma T, Hwang Y, Ahn S, Park I, Ikeda W, Kusuhara S, Fukushima Y, Nara H, Sakai H, Fujiwara T, Matsuhita J, Ema M, Hirashima M, Minami T, Shibuya M, Takakura N, Kim P, Miyata T, Ogura Y, Uemura A. Sustained inflammation after pericyte depletion induces irreversible blood-retina barrier breakdown. JCI Insight. Feb 9;2(3) (2017)
Ito S, Izumi Y, Niidome T, Ono Y. Methylcobalamin prevents mutant SOD1-induced motor neuron death in vitro. Neuroreport. Jan Volume 28(2)101–107(2017)
2016
Kojima C, Fusaoka-Nishioka E, Imai T, Nakahira A, Onodera H. Dendrigraft polylysine coated-poly (glycolic acid) fibrous scaffolds for hippocampal neurons. J Biomed Mater Res A. Nov;104(11):2744-50.(2016)
Samata B, Doi D, Nishimura K, Kikuchi T, Watanabe A, Sakamoto Y, Kakuta J, Ono Y, Takahashi J. Purification of functional human ES and iPSC-derived midbrain dopaminergic progenitors using LRTM1. Nat Commun. Oct 14;7(13097) (2016)
Hayashizaki K, Kimura Y M, Tokoyoda K, Hosokawa H, Shinoda K, Hirahara K, Ichikawa T, Onodera A, Hanazawa A, Iwamura C, Kakuta J, Muramoto K, Motohashi S, Tumes J D, Iinuma T, Yamamoto H, Ikehara Y, Okamoto Y, Nakayama T. Myosin light chains 9 and 12 are functional ligands for CD69 that regulate airway inflammation. Sci Immunol. Sep 16;1(3): eaaf9154.(2016)
Kobayashi S, Hida Y, Ishizaki H, Inoue E, Tanaka-Okamoto M, Yamasaki M, Miyazaki T, Fukaya M, Kitajima I, Takai Y, Watanabe M, Ohtsuka T, Manabe T. The active zone protein CAST regulates synaptic vesicle recycling and quantal size in the mouse hippocampus. Eur J Neurosci. Sep;44(5):2272-84.(2016)
2014
Ishii N, Wakita H, Shirato M. Effect of the phosphodiesterase 4 inhibitor E6005 on nerve growth factor elevation in irritated skin of NC/Nga mice. J Dermatol Sci. Dec;76(3):263-4.(2014)
Hagiwara A, Yasumura M, Hida Y, Inoue E, Ohtsuka T. The planar cell polarity protein Vangl2 bidirectionally regulates dendritic branching in cultured hippocampal neurons. Mol Brain. 7(1):79.(2014)
Tanaka K, Shiota J, Mikami M, Inoue Y, Sumida T, Matsumoto I, Muramoto K. The combined effects of iguratimod with anti-TNFα antibody on experimental arthritis models in mice. Inflamm Regen. May;34(3):157-164.(2014)
Nakatani T, Minaki Y, Kumai M, Nitta C, Ono Y. The c-Ski family member and transcriptional regulator Corl2/Skor2 promotes early differentiation of cerebellar Purkinje cells. Dev Biol. Apr 1;388(1):68-80.(2014)
Doi D, Samata B, Katsukawa M, Kikuchi T, Morizane A, Ono Y, Sekiguchi K, Nakagawa M, Parmar M, Takahashi J. Isolation of Human Induced Pluripotent Stem Cell-derived Dopaminergic Progenitors by Cell Sorting for Successful Transplantation. Stem Cell Reports. Mar 6;2(1):337–350.(2014)
Seto Y , Nakatani T , Masuyama N , Taya S , Kumai M , Minaki Y , Hamaguchi A , Inoue YU , Inoue T , Miyashita S , Fujiyama T , Yamada M , Chapman H , Campbell KJ , Magnuson MA , Wright CV , Kawaguchi Y, Ikenaka K , Takebayashi H , Ishiwata S , Ono Y , Hoshino M . Temporal identity transition from Purkinje cell progenitors to GABAergic interneuron progenitors in the cerebellum. Nat Commun. Feb 18;5(3337):(2014)
2013
Yamada T, Kuramitsu K, Rikitsu E, Kurita S, Ikeda W, Takai Y. Nectin and JAM are critical cell adhesion molecules for the apico-basal alignment of adherens and tight junctions in epithelial cells. Genes Cells. Nov;18(11):985-98.(2013)
Kurita S, Yamada T, Rikitsu E, Ikeda W, Takai Y. Binding between the Junctional Proteins Afadin and PLEKHA7 and Implication in the Formation of Adherens Junction in Epithelial Cells. J Biol Chem. Oct 11;288(41):29356-6.(2013)
Yamada A, Inoue E, Deguchi-Tawarada M, Matsui C, Togawa A, Nakatani T, Ono Y, Takai Y. Necl-2/CADM1 interacts with ErbB4 and regulates its activity in GABAergic neurons. Mol Cell Neurosci. Sep;56:234-243.(2013)
Kitagawa Y, Kikuchi S, Arita Y, Nishimura M, Mizuno K, Ogasawara H, Kawano T, Ochiai T, Otsuji E, Imai T. Inhibition of CCL20 increases mortality in models of mouse sepsis with intestinal apoptosis. Surgery. Jul;154(1):78-88.(2013)
Hoshino A, Ueha S, Hanada S, Imai T, Ito M, Yamamoto K, Matsushima K, Yamaguchi A, Iimura T. Roles of chemokine receptor CX3CR1 in maintaining murine bone homeostasis through the regulation of both osteoblasts and osteoclasts. J Cell Sci. Feb 15;126(4):1032-1045.(2013)
2012
Sakane A, Abdallah AAM, Nakano K, Honda K, Ikeda W, Nishikawa Y, Matsumoto M, Matsushita N, Kitamura T, Sasaki T. Rab13 small G protein and junctional Rab13-binding protein (JRAB) orchestrate actin cytoskeletal organization during epithelial junctional development. J Biol Chem. Dec 14;287(51):42455-42468.(2012)
Matsui C, Inoue E, Kakita A, Arita K, Deguchi-Tawarada M, Togawa A, Yamada A, Takai Y, Takahashi H. Involvement of the (gamma)-secretase-mediated EphA4 signaling pathway in synaptic pathogenesis of Alzheimer's disease. Brain Pathol. Nov;22(6):776-787.(2012)
Dieck ST, Specht D, Strenzke N, Hida Y, Krishnamoorthy V, Schmidt K-F, Inoue E, Ishizaki H, Tanaka-Okamoto M, Miyoshi J, Hagiwara A, Brandstatter JH, Lowel S, Gollisch T, Ohtsuka T, Moser T. Deletion of the presynaptic scaffold cast reduces active zone size in rod photoreceptors and impairs visual processing. J Neurosci. Aug 29;32(35):12192-12203.(2012)
Kitagawa M, Takebe A, Ono Y, Imai T, Nakao K, Nishikawa S, Era T. Phf14, a novel regulator of mesenchyme growth via platelet-derived growth factor (PDGF) receptor-(alpha). J Biol Chem. Aug 10;287(33):27983-27996.(2012)
Suzuki F, Kubota T, Miyazaki Y, Ishikawa K, Ebisawa M, Hirohata S, Ogura T, Mizusawa H, Imai T, Miyasaka N, Nanki T. Serum level of soluble CX3CL1/fractalkine is elevated in patients with polymyositis and dermatomyositis, which is correlated with disease activity. Arthritis Res Ther. Mar 6;14(2):R48.(2012)
Mori T, Shimizu N, Jinno-Oue A, Tanaka A, Shinagawa M, Tokizawa S, Akagi T, Hoshino H. Tax1-expressing feline 8C cells are useful to monitor the life cycle of human T-cell leukemia virus type I. J Gen Virol. Mar;93(Pt 3):588-93.(2012)
2011
Fusaoka-Nishioka E, Shimono C, Taniguchi Y, Togawa A, Yamada A, Inoue E, Onodera H, Sekiguchi K, Imai T. Differential effects of laminin isoforms on axon and dendrite development in hippocampal neurons. Neurosci Res. Dec;71(4):421-426.(2011)
Kaneko K, Miyabe Y, Takayasu A, Fukuda S, Miyabe C, Ebisawa M, Yokoyama W, Watanabe K, Imai T, Muramoto K, Terashima Y, Sugihara T, Matsushima K, Miyasaka N, Nanki T. Chemerin activates fibroblast-like synoviocytes in patients with rheumatoid arthritis. Arthritis Res Ther. Sep 29;13(5):Article Number: R158.(2011)
Kiyozumi D, Osada A, Sugimoto N, Weber CN, Ono Y, Imai T, Okada A, Sekiguchi K. Identification of genes expressed during hair follicle induction. J Dermatol. Jul;38(7):674-679.(2011)
Hida Y, Fukaya M, Hagiwara A, Deguchi-Tawarada M, Yoshioka T, Kitajima I, Inoue E, Watanabe M, Ohtsuka T. Prickle2 is localized in the postsynaptic density and interacts with PSD-95 and NMDA receptors in the brain. J Biochem. Jun;149(6):693-700.(2011)
Sasai K, Sukezane T, Yanagita E, Nakagawa H, Hotta A, Itoh T, Akagi T. Oncogene-mediated human lung epithelial cell transformation produces adenocarcinoma phenotypes in vivo. Cancer Res. Apr 1;71(7):2541-2549.(2011)
2010
Tagi T, Matsui T, Kikuchi S, Hoshi S, Ochiai T, Kokuba Y, Kinoshita-Ida Y, Kisumi-Hayashi F, Morimoto K, Imai T, Imoto I, Inazawa J, Otsuji E. Dermokine as a novel biomarker for early-stage colorectal cancer. J Gastroenterol. Dec 2010;45(12):1201-1211.(2010)
Muguruma K, Nishiyama A, Ono Y, Miyawaki H, Mizuhara E, Hori S, Kakizuka A, Obata K, Yanagawa Y, Hirano T, Sasai Y. Ontogeny-recapitulating generation and tissue integration of ES cell-derived Purkinje cells. Nat Neurosci. Oct 2010;13(10):1171-1180.(2010)
Tanji M, Ishizaki T, Ebrahimi S, Tsuboguchi Y, Sukezane T, Akagi T, Frame MC, Hashimoto N, Miyamoto S, Narumiya S. mDia1 targets v-Src to the cell periphery and facilitates cell transformation, tumorigenesis, and invasion. Mol Cell Biol. Oct 30;19:4604-15.(2010)
Hoshino A, Iimura T, Ueha S, Hanada S, Maruoka Y, Mayahara M, Suzuki K, Imai T, Ito M, Manome Y, Yasuhara M, Kirino T, Yamaguchi A, Matsushima K, Yamamotoa K.
Deficiency of chemokine receptor CCR1 causes osteopenia due to impaired functions of osteoclasts and osteoblasts. J Biol Chem. Sep 10;285(37):28826-28837.(2010)
Miyata T, Ono Y, Okamoto M, Masaoka M, Sakakibara A, Kawaguchi A, Hashimoto M, Ogawa M. Migration, early axonogenesis, and Reelin-dependent layer-forming behavior of early/posterior-born Purkinje cells in the developing mouse lateral cerebellum. Neural Dev. Sep;5:23.(2010)
Kaieda S, Matsui C, Mimori-Kiyosue Y, Ikegami T. Structural basis of the recognition of the samp motif of adenomatous polyposis coli by the src-homology 3 domain. Biochemistry. Jun 29;49(25):5143-5153.(2010)
Ono Y, Nakatani T, Minaki Y, Kumai M. The basic helix-loop-helix transcription factor Nato3 controls neurogenic activity in mesencephalic floor plate cells. Development. Jun 1;137(11):1897-1906.(2010)
Hotta A, Kawakatsu T, Nakatani T, Sato T, Matsui C, Sukezane T, Akagi T, Hamaji T, Grigoriev I, Akhmanova A, Takai Y, Mimori-Kiyosue Y. Laminin-based cell adhesion anchors microtubule plus ends to the epithelial cell basal cortex through LL5(alpha)/(beta). J Cell Biol. May 31;189(5):901-917.(2010)
Muto S, Hata M, Taniguchi J, Tsuruoka S, Moriwaki K, Saitou M, Furuse K, Sasaki H, Fujimura A, Imai M, Kusano E, Tsukita S, Furuse M. Claudin-2-deficient mice are defective in the leaky and cation-selective paracellular permeability properties of renal proximal tubules. Proc Natl Acad Sci U S A. Apr 27;107(17):8011-8016.(2010)
Masuda K, Katagiri C, Nomura M, Sato M, Kakumoto K, Akagi T, Kikuchi K, Tanuma N, Shima H. MKP-7, a JNK phosphatase, blocks ERK-dependent gene activation by anchoring phosphorylated ERK in the cytoplasm. Biochem Biophys Res Commun. Mar 5;393(2):201-6.(2010)
Nakatani T, Kumai M, Mizuhara E, Minaki Y, Ono Y. Lmx1a and Lmx1b cooperate with Foxa2 to coordinate the specification of dopaminergic neurons and control of floor plate cell differentiation in the developing mesencephalon. Dev Biol. Mar 1;339(1):101-113.(2010)
Mizuhara E, Minaki Y, Nakatani T, Kumai M, Inoue T, Muguruma K, Sasai Y, Ono Y. Purkinje cells originate from cerebellar ventricular zone progenitors positive for Neph3 and E-cadherin. Dev Biol. Feb 15;338(2):202-214.(2010)
2009
Koizumi K, Saitoh Y, Minami T, Takeno N, Tsuneyama K, Miyahara T, Nakayama T, Sakurai H, Takano Y, Nishimura M, Imai T, Yoshie O, Saiki I. Role of CX3CL1/fractalkine in osteoclast differentiation and bone resorption. J Immunol. Dec 15;183(12):7825-7831.(2009)
Jonsson M.E, Ono Y, Bjorklund A, Thompson L.H. Identification of transplantable dopamine neuron precursors at different stages of midbrain neurogenesis. Exp Neurol. Sep;219(1):341-354.(2009)
Mori D, Yamada M, Mimori-Kiyosue Y, Shirai Y, Suzuki A, Ohno S, Saya H, Wynshaw-Boris A, Hirotsune S. An essential role of the aPKC-Aurora A-NDEL1 pathway in neurite elongation by modulation of microtubule dynamics. Nat Cell Biol. Aug;11(9):1057-1068.(2009)
Inoue E, Deguchi-Tawarada M, Togawa A, Matsui C, Arita K, Katahira-Tayama S, Sato T, Yamauchi E, Oda Y, Takai Y. Synaptic activity prompts (gamma)-secretase-mediated cleavage of EphA4 and dendritic spine formation. J Cell Biol. May 4;185(3):551-564.(2009)
Tanaka-Okamoto M, Hori K, Ishizaki H, Hosoi A, Itoh Y, Wei M, Wanibuchi H, Mizoguchi A, Nakamura H, Miyoshi J. Increased susceptibility to spontaneous lung cancer in mice lacking LIM-domain only 7. Cancer Sci. Apr;100(4):608-616.(2009)
Abe A, Fukui H, Fujii S, Kono T, Mukawa K, Yoshitake N, Sekikawa A, Ichikawa K, Tomita S, Yamagishi H, Imai Y, Shinoda M, Ishizaki H, Tanaka-Okamoto M, Kubota K, Miyoshi J, Takai Y, Fujimori T. Role of Necl-5 in the pathophysiology of colorectal lesions induced by dimethylhydrazine and/or dextran sodium sulphate. J Pathol. Jan;217(1):42-53.(2009)
2008
Matsui C, Kaieda S, Ikegami T, Mimori-Kiyosue Y. Identification of a link between the SAMP repeats of adenomatous polyposis coli tumor suppressor and the Src homology 3 domain of DDEF. J Biol Chem. Nov 21;283(47):33006-33020.(2008)
Yamada M, Toba S, Yoshida Y, Haratani K, Mori D, Yano Y, Mimori-Kiyosue Y, Nakamura T, Itoh K, Fushiki S, Setou M, Wynshaw-Boris A, Torisawa T, Toyoshima YY, Hirotsune S. LIS1 and NDEL1 coordinate the plus-end-directed transport of cytoplasmic dynein. EMBO J. Oct 8;27(19):2471-2483.(2008)
Minaki Y, Nakatani T, Mizuhara E, Inoue T, Ono Y. Identification of a novel transcriptional corepressor, Corl2, as a cerebellar Purkinje cell-selective marker. Gene Expr Patterns. Jul;8(6):418-423.(2008)
Fujiwara T, Kawakatsu T, Tayama S, Kobayashi Y, Sugiura N, Kimata K, Takai Y. Hyaluronan-CD44 pathway regulates orientation of mitotic spindle in normal epithelial cells. Genes Cells. Jul;13(7):759-770.(2008)
Holmes FE, Arnott N, Vanderplank P, Kerr NCH, Longbrake EE, Popovich PG, Imai T, Combadiere C, Murphy PM, Wynick D. Intra-neural administration of fractalkine attenuates neuropathic pain-related behaviour. J Neurochem. Jul;106(2):640-649.(2008)
Katsuno T, Umeda K, Matsui T, Hata M, Tamura A, Itoh M, Takeuchi K, Fujimori T, Nabeshima YI, Noda T, Tsukita S, Tsukita S. Deficiency of zonula occludens-1 causes embryonic lethal phenotype associated with defected yolk sac angiogenesis and apoptosis of embryonic cells. Mol Biol Cell. Jun;19(6):2465-2475.(2008)
Amano H, Ikeda W, Kawano S, Kajita M, Tamaru Y, Inoue N, Minami Y, Yamada A, Takai Y. Interaction and localization of Necl-5 and PDGF receptor (beta) at the leading edges of moving NIH3T3 cells: Implications for directional cell movement. Genes Cells. Mar;13(3):269-284.(2008)
Morimoto K, Satoh-Yamaguchi K, Hamaguchi A, Inoue Y, Takeuchi M, Okada M, Ikeda W, Takai Y, Imai T. Interaction of cancer cells with platelets mediated by Necl-5/poliovirus receptor enhances cancer cell metastasis to the lungs. Oncogene. Jan 10;27(3):264-273.(2008)
Hayashi H, Morizane A, Koyanagi M, Ono Y, Sasai Y, Hashimoto N, Takahashi J. Meningeal cells induce dopaminergic neurons from embryonic stem cells. Eur J Neurosci. Jan;27(2):261-268.(2008)
2007
Nishimura K, Kitamura Y, Inoue T, Umesono Y, Sano S, Yoshimoto K, Inden M, Takata K, Taniguchi T, Shimohama S, Agata K. Reconstruction of dopaminergic neural network and locomotion function in planarian regenerates. Dev Neurobiol. July;67(8):1059-1078.(2007)
Kobayashi T, Okamoto S, Iwakami Y, Nakazawa A, Hisamatsu T, Chinen H, Kamada N, Imai T, Goto H, Hibi T. Exclusive increase of CX3CR1(+)CD28(-)CD4(+) T cells in inflammatory bowel disease and their recruitment as intraepithelial lymphocytes. Inflamm Bowel Dis. July;13(7):837-846.(2007)
Mizutani N, Sakurai T, Shibata T, Uchida K, Fujita J, Kawashima R, Kawamura YI, Toyama-Sorimachi N, Imai T, Dohi T. Dose-dependent differential regulation of cytokine secretion from macrophages by fractalkine. J Immunol. Dec 1;179(11):7478-7487.(2007)
Ono Y, Nakatani T, Sakamoto Y, Mizuhara E, Minaki Y, Kumai M, Hamaguchi A, Nishimura M, Inoue Y, Hayashi H, Takahashi J, Imai T. Differences in neurogenic potential in floor plate cells along an anteroposterior location: Midbrain dopaminergic neurons originate from mesencephalic floor plate cells. Development. Sep;134(17):3213-3225.(2007)
Nishimura K, Kitamura Y, Inoue T, Umesono Y, Yoshimoto K, Takeuchi K, Taniguchi T, Agata K. Identification and distribution of tryptophan hydroxylase (TPH)-positive neurons in the planarian Dugesia japonica. Neurosci Res. Sep;59(1):101-106.(2007)
Kotake Y, Sagane K, Owa T, Mimori-Kiyosue Y, Shimizu H, Uesugi M, Ishihama Y, Iwata M, Mizui Y. Splicing factor SF3b as a target of the antitumor natural product pladienolide. Nat Chem Biol. Sep;3(9):570-575.(2007)
Nakatani T, Minaki Y, Kumai M, Ono Y. Helt determines GABAergic over glutamatergic neuronal fate by repressing Ngn genes in the developing mesencephalon. Development. Aug;134(15):2783-2793.(2007)
Takahashi K, Yoshida N, Murakami N, Kawata K, Ishizaki H, Tanaka-Okamoto M, Miyoshi J, Zinn AR, Shime H, Inoue N. Dynamic regulation of p53 subnuclear localization and senescence by MORC3. Mol Biol Cell. May;18(5):1701-1709.(2007)
Inoue T, Hayashi T, Takechi K, Agata K. Clathrin-mediated endocytic signals are required for the regeneration of, as well as homeostasis in, the planarian CNS. Development. May;134(9):1679-1689.(2007)
Sugihara-Mizuno Y, Adachi M, Kobayashi Y, Hamazaki Y, Nishimura M, Imai T, Furuse M, Tsukita S. Molecular characterization of angiomotin/JEAP family proteins: Interaction with MUPP1/Patj and their endogenous properties. Genes Cells. Apr;12(4):473-486.(2007)
Higa S, Tokoro T, Inoue E, Kitajima I, Ohtsuka T. The active zone protein CAST directly associates with Ligand-of-Numb protein X. Biochem Biophys Res Commun. Mar 16;354(3):686-692.(2007)
Tokoro T, Higa S, Deguchi M, Inoue E, Kitajima I, Ohtsuka T. Localization of the active zone proteins CAST, ELKS, and Piccolo at neuromuscular junctions. Neuroreport. Mar 5;18(4):313-6.(2007)
Fukumoto K, Kikuchi S, Itoh N, Tamura A, Hata M, Yamagishi H, Tsukita S, Tsukita S. Effects of genetic backgrounds on hyperbilirubinemia in radixin-deficient mice due to different expression levels of Mrp3. Bba-Mol Basis Dis. Mar;1772(3):298-306.(2007)
Mimori-Kiyosue Y, Matsui C, Sasaki H, Tsukita S. Adenomatous polyposis coli (APC) protein regulates epithelial cell migration and morphogenesis via PDZ domain-based interactions with plasma membranes. Genes Cells. Feb;12(2):219-233.(2007)
Nishimoto G, Sasaki G, Yaoita E, Nameta M, Li H, Furuse K, Fujinaka H, Yoshida Y, Mitsudome A, Yamamoto T. Molecular characterization of water-selective AQP (EbAQP4) in hagfish: Insight into ancestral origin of AQP4. Am J Physiol-Reg I. Jan;292(1):R644-R651.(2007)
Ueha S, Murai M, Yoneyama H, Kitabatake M, Imai T, Shimaoka T, Yonehara S, Ishikawa S, Matsushima K. Intervention of MAdCAM-1 or fractalkine alleviates graft-versus-host reaction associated intestinal injury while preserving graft-versus-tumor effects. J Leukoc Biol. Jan;81(1):176-185.(2007)
2006
Lansbergen G, Grigoriev I, Mimori-Kiyosue Y, Ohtsuka T, Higa S, Kitajima I, Demmers J, Galjart N, Houtsmuller AB, Grosveld F, Akhmanova A. CLASPs Attach Microtubule Plus Ends to the Cell Cortex through a Complex with LL5(beta). Dev Cell. July;11(1):21-32.(2006)
Ishizaki H, Togawa A, Tanaka-Okamoto M, Hori K, Nishimura M, Hamaguchi A, Imai T, Takai Y, Miyoshi J. Defective chemokine-directed lymphocyte migration and development in the absence of Rho guanosine diphosphate-dissociation inhibitors (alpha) and (beta). J Immunol. Dec 15;177(12):8512-8521.(2006)
Adachi M, Inoko A, Hata M, Furuse K, Umeda K, Itoh M, Tsukita S. Normal establishment of epithelial tight junctions in mice and cultured cells lacking expression of ZO-3, a tight-junction MAGUK protein. Mol Cell Biol. Dec;26(23):9003-9015.(2006)
Matsui T, Kinoshita-Ida Y, Hayashi-Kisumi F, Hata M, Matsubara K, Chiba M, Katahira-Tayama S, Morita K, Miyachi Y, Tsukita S. Mouse homologue of skin-specific retroviral-like aspartic protease involved in wrinkle formation. J Biol Chem. Sep 15;281(37):27512-27525.(2006)
Inagaki M, Irie K, Ishizaki H, Tanaka-okamoto M, Miyoshi J, Takai Y. Role of cell adhesion molecule nectin-3 in spermatid development. Genes Cells. Sep;11(9):1125-1132.(2006)
Umeda K, Ikenouchi J, Katahira-Tayama S, Furuse K, Sasaki H, Matsui T, Tsukita S, Furuse M, Tsukita S. ZO-1 and ZO-2 Independently Determine Where Claudins Are Polymerized in Tight-Junction Strand Formation. Cell. Aug 25;126(4):741-754.(2006)
Yamada A, Fujita N, Sato T, Okamoto R, Ooshio T, Hirota T, Morimoto K, Irie K, Takai Y. Requirement of nectin, but not cadherin, for formation of claudin-based tight junctions in annexin II-knockdown MDCK cells. Oncogene. Aug 24;25(37):5085-5102.(2006)
Mimori-Kiyosue Y, Grigoriev I, Sasaki H, Matsui C, Akhmanova A, Tsukita S, Vorobjev I. Mammalian CLASPs are required for mitotic spindle organization and kinetochore alignment. Genes Cells. Aug;11(8):845-857.(2006)
Inoue E, Deguchi-Tawarada M, Takao-Rikitsu E, Inoue M, Kitajima I, Ohtsuka T, Takai Y. ELKS, a protein structurally related to the active zone protein CAST, is involved in Ca(2+)-dependent exocytosis from PC12 cells. Genes Cells. Jun;11(6):659-672.(2006)
Fusaoka E, Inoue T, Mineta K, Agata K, Takeuchi K. Structure and function of primitive immunoglobulin superfamily neural cell adhesion molecules: A lesson from studies on planarian. Genes Cells. May;11(5):541-555.(2006)
Inoue E, Mochida S, Takagi H, Higa S, Deguchi-Tawarada M, Takao-Rikitsu E, Inoue M, Yao I, Takeuchi K, Kitajima I, Setou M, Ohtsuka T, Takai Y. SAD: A Presynaptic Kinase Associated with Synaptic Vesicles and the Active Zone Cytomatrix that Regulates Neurotransmitter Release. Neuron. Apr 20;50(2):261-275.(2006)
Ohmori K, Fukui F, Kiso M, Imai T, Yoshie O, Hasegawa H, Matsushima K, Kannagi R. Identification of cutaneous lymphocyte-associated antigen as sialyl 6-sulfo Lewis X, a selectin ligand expressed on a subset of skin-homing helper memory T cells. Blood. Apr 15;107(8):3197-3204.(2006)
Deguchi-Tawarada M, Inoue E, Takao-Rikitsu E, Inoue M, Kitajima I, Ohtsuka T, Takai Y. Active zone protein CAST is a component of conventional and ribbon synapses in mouse retina. J Comp Neurol. Apr 1;495(4):480-496.(2006)
Honda T, Sakisaka T, Yamada T, Kumazawa N, Hoshino T, Kajita M, Kayahara T, Ishizaki H, Tanaka-Okamoto M, Mizoguchi A, Manabe T, Miyoshi J, Takai Y. Involvement of nectins in the formation of puncta adherentia junctions and the mossy fiber trajectory in the mouse hippocampus. Mol Cell Neurosci. Feb;31(2):315-325.(2006)
2005
Ikenouchi J, Furuse M, Furuse K, Sasaki H, Tsukita S, Tsukita S. Tricellulin constitutes a novel barrier at tricellular contacts of epithelial cells. J Cell Biol. Dec 19;171(6):939-945.(2005)
Suzuki F, Nanki T, Imai T, Kikuchi H, Hirohata S, Kohsaka H, Miyasaka N. Inhibition of CX3CL1 (fractalkine) improves experimental autoimmune myositis in SJL/J mice. J Immunol. Nov 15;175(10):6987-6996.(2005)
Komiya S, Shimizu M, Ikenouchi J, Yonemura S, Matsui T, Fukunaga Y, Liu H, Endo F, Tsukita S, Nagafuchi A. Apical membrane and junctional complex formation during simple epithelial cell differentiation of F9 cells. Genes Cells. Nov;10(11):1065-1080.(2005)
Hagiwara A, Fukazawa Y, Deguchi-Tawarada M, Ohtsuka T, Shigemoto R. Differential distribution of release-related proteins in the hippocampal CA3 area as revealed by freeze-fracture replica labeling. J Comp Neurol. Aug 22;489(2):195-216.(2005)
Mizuhara E, Nakatani T, Minaki Y, Sakamoto Y, Ono Y, Takai Y. MAGI1 recruits Dll1 to cadherin-based adherens junctions and stabilizes it on the cell surface. J Biol Chem. Jul 15;280(28):26499-26507.(2005)
Kawagishi R, Tahara M, Morishige K, Sakata M, Tasaka K, Ikeda W, Morimoto K, Takai Y, Murata Y. Expression of nectin-2 in mouse granulosa cells. Eur J Obstet Gyn R B. Jul 1;121(1):71-76.(2005)
Minaki Y, Mizuhara E, Morimoto K, Nakatani T, Sakamoto Y, Inoue Y, Satoh K, Imai T, Takai Y, Ono Y. Migrating postmitotic neural precursor cells in the ventricular zone extend apical processes and form adherens junctions near the ventricle in the developing spinal cord. Neurosci Res. Jul;52(3):250-262.(2005)
Ohara-Imaizumi M, Ohtsuka T, Matsushima S, Akimoto Y, Nishiwaki C, Nakamichi Y, Kikuta T, Nagai S, Kawakami H, Watanabe T, Nagamatsu S. ELKS, a protein structurally related to the active zone-associated protein CAST, is expressed in pancreatic (beta) cells and functions in insulin exocytosis: Interaction of ELKS with exocytotic machinery analyzed by total internal reflection fluorescence microscopy. Mol Biol Cell. Jul;16(7):3289-3300.(2005)
Kanaya H, Takeya R, Takeuchi K, Watanabe N, Jing N, Sumimoto H. Fhos2, a novel formin-related actin-organizing protein, probably associates with the nestin intermediate filament. Genes Cells. Jul;10(7):665-678.(2005)
Yuba-Kubo A, Kubo A, Hata M, Tsukita S. Gene knockout analysis of two (gamma)-tubulin isoforms in mice. Dev Biol. Jun 15;282(2):361-373.(2005)
Kiyozumi D, Osada A, Sugimoto N, Weber CN, Ono Y, Imai T, Okada A, Sekiguchi K. Identification of a novel cell-adhesive protein spatiotemporally expressed in the basement membrane of mouse developing hair follicle. Exp Cell Res. May 15;306(1):9-23.(2005)
Miyamoto T, Morita K, Takemoto D, Takeuchi K, Kitano Y, Miyakawa T, Nakayama K, Okamura Y, Sasaki H, Miyachi Y, Furuse M, Tsukita S. Tight junctions in Schwann cells of peripheral myelinated axons: A lesson from claudin-19-deficient mice. J Cell Biol. May 9;169(3):527-538.(2005)
Miyazaki T, Ono M, Qu W-M, Zhang M-C, Mori S, Nakatsuru S, Nakamura Y, Sawasaki T, Endo Y, Nose M. Implication of allelic polymorphism of osteopontin in the development of lupus nephritis in MRL/lpr mice. Eur J Immunol. May;35(5):1510-1520.(2005)
Sawai H, Park YW, Roberson J, Imai T, Goronzy JJ, Weyand CM. T cell costimulation by fractalkine-expressing synoviocytes in rheumatoid arthritis. Arthritis Rheum. May;52(5):1392-1401.(2005)
Inoue A, Hasegawa H, Kohno M, Ito MR, Terada M, Imai T, Yoshie O, Nose M, Fujita S. Antagonist of fractalkine (CX3CL1) delays the initiation and ameliorates the progression of lupus nephritis in MRL/lpr mice. Arthritis Rheum. May;52(5):1522-1533.(2005)
Okamoto K, Takeuchi K, Agata K. Neural projections in planarian brain revealed by fluorescent dye tracing. Zoolog Sci. May;22(5):535-546.(2005)
Tamura A, Kikuchi S, Hata M, Katsuno T, Matsui T, Hayashi H, Suzuki Y, Noda T, Tsukita S, Tsukita S. Achlorhydria by ezrin knockdown: Defects in the formation/expansion of apical canaliculi in gastric parietal cells. J Cell Biol. Apr 11;169(1):21-28.(2005)
Sasakura H, Inada H, Kuhara A, Fusaoka E, Takemoto D, Takeuchi K, Mori I. Maintenance of neuronal positions in organized ganglia by SAX-7, a Caenorhabditis elegans homologue of L1. EMBO J. Apr 6;24(7):1477-1488.(2005)
Inagaki M, Irie K, Ishizaki H, Tanaka-Okamoto M, Morimoto K, Inoue E, Ohtsuka T, Miyoshi J, Takai Y. Roles of cell-adhesion molecules nectin 1 and nectin 3 in ciliary body development. Development. Apr;132(7):1525-1537.(2005)
Li H-P, Honma S, Miki T, Takeuchi Y, Takeuchi K, Kawano H. Multiple defects in the formation of rat cortical axonal pathways following prenatal X-ray irradiation. Eur J Neurosci. Apr;21(7):1847-1858.(2005)
Nakamura H, Mukai M, Komatsu K, Tanaka-Okamoto M, Itoh Y, Ishizaki H, Tatsuta M, Inoue M, Miyoshi J. Transforming growth factor-(beta)1 induces LMO7 while enhancing the invasiveness of rat ascites hepatoma cells. Cancer Lett. Mar 18;220(1):95-99.(2005)
Kakunaga S, Ikeda W, Itoh S, Deguchi-Tawarada M, Ohtsuka T, Mizoguchi A, Takai Y. Nectin-like molecule-1/TSLL1/SynCAM3: A neural tissue-specific immunoglobulin-like cell-cell adhesion molecule localizing at non-junctional contact sites of presynaptic nerve terminals, axons and glia cell processes. J Cell Sci. Mar 15;118(6):1267-1277.(2005)
Mizuhara E, Nakatani T, Minaki Y, Sakamoto Y, Ono Y. Corl1, a novel neuronal lineage-specific transcriptional corepressor for the homeodomain transcription factor Lbx1. J Biol Chem. Feb 4;280(5):3645-3655.(2005)
Osada A, Kiyozumi D, Tsutsui K, Ono Y, Weber CN, Sugimoto N, Imai T, Okada A, Sekiguchi K. Expression of MAEG, a novel basement membrane protein, in mouse hair follicle morphogenesis. Exp Cell Res. Feb 1;303(1):148-159.(2005)
Mimori-Kiyosue Y, Grigoriev I, Lansbergen G, Sasaki H, Matsui C, Severin F, Galjart N, Grosveld F, Vorobjev I, Tsukita S, Akhmanova A. CLASP1 and CLASP2 bind to EB1 and regulate microtubule plus-end dynamics at the cell cortex. J Cell Biol. Jan 3;168(1):141-153.(2005)
2004
Nanki T, Urasaki Y, Imai T, Nishimura M , Muramoto K, Kubota T, Miyasaka N. Inhibition of fractalkine ameliorates murine collagen-induced arthritis. J Immunol. Dec 1;173(11):7010-7016.(2004)
Ohnishi H, Nakahara T, Furuse K, Sasaki H, Tsukita S, Furuse M. JACOP, a novel plaque protein localizing at the apical junctional complex with sequence similarity to cingulin. J Biol Chem. Oct 29;279(44):46014-46022.(2004)
Umeda K, Matsui T, Nakayama M, Furuse E, Sasaki H, Furuse M, Tsukita S. Establishment and characterization of cultured epithelial cells lacking expression of ZO-1. J Biol Chem. Oct 22;279(43):44785-44794.(2004)
Kitajiri SI, Miyamoto T, Mineharu A, Sonoda N, Furuse K, Hata M, Sasaki H, Mori Y, Kubota T, Ito J, Furuse M, Tsukita S. Compartmentalization established by claudin-11-based tight junctions in stria vascularis is required for hearing through generation of endocochlear potential. J Cell Sci. Oct 1;117(21):5087-5096.(2004)
Okabe N, Shimizu K, Ozaki-Kuroda K, Nakanishi H, Morimoto K, Takeuchi M, Katsumaru H, Murakami F, Takai Y. Contacts between the commissural axons and the floor plate cells are mediated by nectins. Dev Biol. Sep 15;273(2):244-256.(2004)
Sugimoto K, Ohata M, Miyoshi J, Ishizaki H, Tsuboi N, Masuda A, Yoshikai Y, Takamoto M, Sugane K, Matsuo S, Shimada Y, Matsuguchi T. A serine/threonine kinase, Cot/Tpl2, modulates bacterial DNA-induced IL-12 production and Th cell differentiation. J Clin Investig. Sep;114(6):857-866.(2004)
Kakunaga S, Ikeda W, Shingai T, Fujito T, Yamada A, Minami Y, Imai T, Takai Y. Enhancement of serum- and platelet-derived growth factor-induced cell proliferation by Necl-5/Tage4/poliovirus receptor/CD155 through the Ras-Raf-MEK-ERK signaling. J Biol Chem. Aug 27;279(35):36419-36425.(2004)
Kitajiri SI, Fukumoto K, Hata M, Sasaki H, Katsuno T, Nakagawa T, Ito J, Tsukita S, Tsukita S. Radixin deficiency causes deafness associated with progressive degeneration of cochlear stereocilia. J Cell Biol. Aug 16;166(4):559-570.(2004)
Matsui T, Hayashi-Kisumi F, Kinoshita Y , Katahira S, Morita K, Miyachi Y, Ono Y, Imai T, Tanigawa Y, Komiya T, Tsukita S. Identification of novel keratinocyte-secreted peptides dermokine-(alpha)/- (beta) and a new stratified epithelium-secreted protein gene complex on human chromosome 19q13.1. Genomics. Aug;84(2):384-397.(2004)
Ooshio T, Irie K, Morimoto K, Fukuhara A, Imai T, Takai Y. Involvement of LMO7 in the association of two cell-cell adhesion molecules, nectin and E-cadherin, through afadin and (alpha)-actinin in epithelial cells. J Biol Chem. Jul 23;279(30):31365-31373.(2004)
Izumi G, Sakisaka T, Baba T, Tanaka S, Morimoto K, Takai Y. Endocytosis of E-cadherin regulated by Rac and Cdc42 small G proteins through IQGAP1 and actin filaments. J Cell Biol. Jul 19;166(2):237-248.(2004)
Ikeda W, Kakunaga S, Takekuni K, Shingai T, Satoh K, Morimoto K, Takeuchi M, Imai T, Takai Y. Nectin-like Molecule-5/Tage4 Enhances Cell Migration in an Integrin-dependent, Nectin-3-independent Manner. J Biol Chem. Apr 23;279(17):18015-18025.(2004)
Nakatani T, Mizuhara E, Minaki Y, Sakamoto Y, Ono Y. Helt, a Novel Basic-Helix-Loop-Helix Transcriptional Repressor Expressed in the Developing Central Nervous System. J Biol Chem. Apr 16;279(16):16356-16367.(2004)
Yoshikawa M, Nakajima T, Matsumoto K, Okada N, Tsukidate T, Iida M, Otori N, Haruna SI, Moriyama H, Imai T, Saito H. TNF-(alpha) and IL-4 regulate expression of fractalkine (CX(3)CL1) as a membrane-anchored proadhesive protein and soluble chemotactic peptide on human fibroblasts. FEBS Lett. Mar 12;561(1-3):105-110.(2004)
Ohtani N, Ohtani H, Nakayama T, Naganuma H, Sato E, Imai T, Nagura H, Yoshie O. Infiltration of CD8+ T cells containing RANTES/CCL5+ cytoplasmic granules in actively inflammatory lesions of human chronic gastritis. Lab Invest. Mar;84(3):368-375.(2004)
Takao-Rikitsu E, Mochida S, Inoue E, Deguchi-Tawarada M, Inoue M, Ohtsuka T, Takai Y. Physical and functional interaction of the active zone proteins, CAST, RIM1, and Bassoon, in neurotransmitter release. J Cell Biol. Jan 19;164(2):301-311.(2004)
Deguchi-Tawarada M, Inoue E, Takao-Rikitsu E, Inoue M, Ohtsuka T, Takai Y. CAST2: Identification and characterization of a protein structurally related to the presynaptic cytomatrix protein CAST. Genes Cells. Jan;9(1):15-23.(2004)
2003
Yamada A, Irie K, Deguchi-Tawarada M, Ohtsuka T, Takai Y. Nectin-dependent localization of synaptic scaffolding molecule (S-SCAM) at the puncta adherentia junctions formed between the mossy fibre terminals and the dendrites of pyramidal cells in the CA3 area of the mouse hippocampus. Genes Cells. Dec;8(12):985-994.(2003)
Shingai T, Ikeda W, Kakunaga S, Morimoto K, Takekuni K, Itoh S, Satoh K, Takeuchi M, Imai T, Monden M, Takai Y. Implications of nectin-like molecule-2/IGSF4/RA175/SgIGSF/TSLC1/SynCAM1 in cell-cell adhesion and transmembrane protein localization in epithelial cells. J Biol Chem. Sep 12;278(37):35421-35427.(2003)
Ikeda W, Kakunaga S, Itoh S, Shingai T, Takekuni K, Satoh K, Inoue Y, Hamaguchi A, Morimoto K, Takeuchi M, Imai T, Takai Y. Tage4/nectin-like molecule-5 heterophilically trans-interacts with cell adhesion molecule nectin-3 and enhances cell migration. J Biol Chem. Jul 25;278(30):28167-28172.(2003)
Asano A, Asano K, Sasaki H, Furuse M, Tsukita S. Claudins in Caenorhabditis elegans: Their distribution and barrier function in the epithelium. Curr Biol. Jun 17;13(12):1042-1046.(2003)
Inagaki M, Irie K, Deguchi-Tawarada M, Ikeda W, Ohtsuka T, Takeuchi M, Takai Y. Nectin-dependent localization of ZO-1 at puncta adhaerentia junctions between the mossy fiber terminals and the dendrites of the pyramidal cells in the CA3 area of adult mouse hippocampus. J Comp Neurol. Jun 9;460(4):514-524.(2003)
Kawabe H, Sakisaka T, Yasumi M, Shingai T, Izumi G, Nagano F, Deguchi-Tawarada M, Takeuchi M, Nakanishi H, Takai Y. A novel rabconnectin-3-binding protein that directly binds a GDP/GTP exchange protein for Rab3A small G protein implicated in Ca(2+)-dependent exocytosis of neurotransmitter. Genes Cells. Jun 1;8(6):537-546.(2003)
Morita K, Sasaki H, Furuse K, Furuse M, Tsukita S, Miyachi Y. Expression of claudin-5 in dermal vascular endothelia. Exp Dermatol. Jun;12(3):289-295.(2003)
Nitta T, Hata M, Gotoh S, Seo Y, Sasaki H, Hashimoto N, Furuse M, Tsukita S. Size-selective loosening of the blood-brain barrier in claudin-5-deficient mice. J Cell Biol. May 12;161(3):653-660.(2003)
Yamada A, Miyazaki T, Lu L-M, Ono M, Ito MR, Terada M, Mori S, Hata K, Nozaki Y, Nakatsuru S, Nakamura Y, Onji M, Nose M. Genetic basis of tissue specificity of vasculitis in MRL/lpr mice. Arthritis Rheum. May 1;48(5):1445-1451.(2003)
Sasaki H, Matsui C, Furuse K, Mimori-Kiyosue Y, Furuse M, Tsukita S. Dynamic behavior of paired claudin strands within apposing plasma membranes. Proc Natl Acad Sci U S A. Apr 1;100(7):3971-3976.(2003)
Yasumi M, Shimizu K, Honda T, Takeuchi M, Takai Y. Role of each immunoglobulin-like loop of nectin for its cell-cell adhesion activity. Biochem Biophys Res Commun. Feb 28;302(1):61-66.(2003)
Takekuni K, Ikeda W, Fujito T, Morimoto K, Takeuchi M, Monden M, Takai Y. Direct binding of cell polarity protein PAR-3 to cell-cell adhesion molecule nectin at neuroepithelial cells of developing mouse. J Biol Chem. Feb 21;278(8):5497-5500.(2003)
Asada M, Irie K, Morimoto K, Yamada A, Ikeda W, Takeuchi M, Takai Y. ADIP, a novel afadin- and (alpha)-actinin-binding protein localized at cell-cell adherens junctions. J Biol Chem. Feb 7;278(6):4103-4111.(2003)
Yoneda O, Imai T, Nishimura M, Miyaji M, Mimori T, Okazaki T, Domae N, Fujimoto H, Minami Y, Kono T, Bloom E.T, Umehara H. Membrane-bound form of fractalkine induces IFN- production by NK cells. Eur J Immunol. Jan 1;33(1):53-58.(2003)
Katayama H, Satoh K, Takeuchi M, Deguchi-Tawarada M, Oda Y, Nagasu T. Optimization of in-gel protein digestion system in combination with thin-gel separation and negative staining in 96-well plate format. Rapid Commun Mass Spectrom. 17(10):1071-1078.(2003)
2002
Kikuchi S, Hata M, Fukumoto K, Yamane Y, Matsui T, Tamura A, Yonemura S, Yamagishi H, Keppler D, Tsukita S, Tsukita S. Radixin deficiency causes conjugated hyperbilirubinemia with loss of Mrp2 from bile canalicular membranes. Nat Genet. July;31(3):320-325.(2002)
Nanki T, Imai T, Nagasaka K, Urasaki Y, Nonomura Y, Taniguchi K, Hayashida K, Hasegawa J, Yoshie O, Miyasaka N. Migration of CX3CR1-positive T cells producing type 1 cytokines and cytotoxic molecules into the synovium of patients with rheumatoid arthritis. Arthritis Rheum. Nov 1;46(11):2878-2883.(2002)
Ohtsuka T, Takao-Rikitsu E, Inoue E, Inoue M, Takeuchi M, Matsubara K, Deguchi-Tawarada M, Satoh K, Morimoto K, Nakanishi H, Takai Y. CAST: A novel protein of the cytomatrix at the active zone of synapses that forms a ternary complex with RIM1 and Munc13-1. J Cell Biol. Aug;158(3):577-590.(2002)
Yonemura S, Matsui T, Tsukita S, Tsukita S. Rho-dependent and -indenpendent activation mechanisms of ezrin/radixin/moesin proteins: An essential role for polyphosphoinositides in vivo. J Cell Sci. Jun 15;115(12):2569-2580.(2002)
Nishimura M, Umehara H, Nakayama T, Yoneda O, Hieshima K, Kakizaki M, Dohmae N, Yoshie O, Imai T. Dual functions of fractalkine/CX3C ligand 1 in trafficking of perforin(+)/granzyme B(+) cytotoxic effector lymphocytes that are defined by Cx3CR1 expression. J Immunol. Jun 15;168(12):6173-6180.(2002)
Morita K, Furuse M, Yoshida Y, Itoh M, Sasaki H, Tsukita S, Miyachi Y. Molecular architecture of tight junctions of periderm differs from that of the maculae occludentes of epidermis. J Investig Dermatol. Jun;118(6):1073-1079.(2002)
Fong A.M, Alam S.M, Imai T, Haribabu B, Patel D.D. CX3CR1 tyrosine sulfation enhances fractalkine-induced cell adhesion. J Biol Chem. May 31;277(22):19418-19423.(2002)
Kamogawa J, Terada M, Mizuki S, Nishihara M, Yamamoto H, Mori S, Abe Y, Morimoto K, Nakatsuru S, Nakamura Y, Nose M. Arthritis in MRL/lpr mice is under the control of multiple gene loci with an allelic combination derived from the original inbred strains. Arthritis Rheum. Apr;46(4):1067-1074.(2002)
Nagano F, Kawabe H, Nakanishi H, Shinohara M, Deguchi-Tawarada M, Takeuchi M, Sasaki T, Takai Y. Rabconnectin-3, a novel protein that binds both GDP/GTP exchange protein and GTPase-activating protein for Rab3 small G protein family. J Biol Chem. Mar 22;277(12):9629-9632.(2002)
Furuse M, Hata M, Furuse K, Yoshida Y, Haratake A, Sugitani Y, Noda T, Kubo A, Tsukita S. Claudin-based tight junctions are crucial for the mammalian epidermal barrier: A lesson from claudin-1-deficient mice. J Cell Biol. Mar 18;156(6):1099-1111.(2002)
Nishimura M, Kakizaki M, Ono Y, Morimoto K, Takeuchi M, Inoue Y, Imai T, Takai Y. JEAP, a novel component of tight junctions in exocrine cells. J Biol Chem. Feb 15;277(7):5583-5587.(2002)
Mizoguchi A , Nakanishi H, Kimura K, Matsubara K, Ozaki-Kuroda K, Katata T., Honda T, Kiyohara Y, Heo K, Higashi M, Tsutsumi T, Sonoda S, Ide C, Takai Y. Nectin: An adhesion molecule involved in formation of synapses. J Cell Biol. Feb 4;156(3):555-565.(2002)
Satoh K, Takeuchi M, Oda Y, Deguchi-Tawarada M, Sakamoto Y, Matsubara K, Nagasu T, Takai Y. Identification of activity-regulated proteins in the postsynaptic density fraction. Genes Cells. Feb;7(2):187-197.(2002)
Hamazaki Y, Itoh M, Sasaki H, Furuse M, Tsukita S. Multi-PDZ domain protein 1 (MUPP1) is concentrated at tight junctions through its possible interaction with claudin-1 and junctional adhesion molecule. J Biol Chem. Jan 4;277(1):455-461.(2002)
2001
Kawabe H, Nakanishi H, Asada M, Fukuhara A, Morimoto K, Takeuchi M, Takai Y. Pilt, a Novel Peripheral Membrane Protein at Tight Junctions in Epithelial Cells. J Biol Chem. Dec 21;276(51):48350-48355.(2001)
Itoh M, Sasaki H, Furuse M, Ozaki H, Kita T, Tsukita S. Junctional adhesion molecule (JAM) binds to PAR-3: A possible mechanism for the recruitment of PAR-3 to tight junctions. J Cell Biol. Aug 6;154(3):491-497.(2001)
Ishikawa H, Tamura A, Matsui T, Sasaki H, Hakoshima T, Tsukita S, Tsukita S. Structural conversion between open and closed forms of radixin: Low-angle shadowing electron microscopy. J Mol Biol. Jul 27;310(5):973-978.(2001)
Harrison J.K, Fong A.M, Swain P.A.W, Chen S, Yu Y-RA, Salafranca M.N, Greenleaf W.B, Imai T, Patel D.D. Mutational analysis of the fractalkine chemokine domain. Basic amino acid residues differentially contribute to CX3CR1 binding, signaling, and cell adhesion. J Biol Chem. Jun 15;276(24):21632-21641.(2001)
Umehara H, Goda S, Imai T, Nagano Y, Minami Y, Tanaka Y, Okazaki T, Bloom E.T, Domae N. Fractalkine, a CX3C-chemokine, functions predominantly as an adhesion molecule in monocytic cell line THP-1. Immunol Cell Biol. Jun;79(3):298-302.(2001)
Hamada K, Seto A, Shimizu T, Matsui T, Takai Y, Tsukita S, Tsukita S, Hakoshima T. Crystallization and preliminary crystallographic studies of RhoGDI in complex with the radixin FERM domain. Acta Crystallogr Sect D Biol Crystallogr. Jun;57(6):889-890.(2001)
Tanaka M, Miyoshi J, Ishizaki H, Togawa A, Ohnishi K, Endo K, Matsubara K, Mizoguchi A, Nagano T, Sato M, Sasaki T, Takai Y. Crystallographic characterization of the radixin FERM domain bound to the cytoplasmic tail of the adhesion protein ICAM-2. Acta Crystallogr Sect D Biol Crystallogr. Jun;57(6):891-892.(2001)
Tanaka M, Miyoshi J, Ishizaki H, Togawa A, Ohnishi K, Endo K, Matsubara K, Mizoguchi A, Nagano T, Sato M, Sasaki T, Takai Y. Role of Rab3 GDP/GTP exchange protein in synaptic vesicle trafficking at the mouse neuromuscular junction. Mol Biol Cell. May;12(5):1421-30.(2001)
Furuse M, Furuse K, Sasaki H, Tsukita S. Conversion of zonulae occludentes from tight to leaky strand type by introducing claudin-2 into Madin-Darby canine kidney I cells. J Cell Biol. Apr 16;153(2):263-272.(2001)
Patel D.D, Koopmann W, Imai T, Whichard L.P, Yoshie O, Krangel M.S. Chemokines have diverse abilities to form solid phase gradients. Clin Immunol. Apr;99(1):43-52.(2001)
Kawasaki S, Takizawa H, Yoneyama H, Nakayama T, Fujisawa R, Izumizaki M, Imai T, Yoshie O, Homma I, Yamamoto K, Matsushima K. Intervention of thymus and activation-regulated chemokine attenuates the development of allergic airway inflammation and hyperresponsiveness in mice. J Immunol. Feb 1;166(3):2055-2062.(2001)
Hashida H, Takabayashi A, Adachi M, Imai T, Kondo K, Kohno N, Yamaoka Y, Miyake M. The novel monoclonal antibody MH8-4 inhibiting cell motility recognizes integrin alpha 3: inverse of its expression withmetastases in colon cancer. Int J Oncol. Jan;18(1):89-95.(2001)
2000
Saitou M, Furuse M, Sasaki H, Schulzke J-D, Fromm M, Takano H, Noda T, Tsukita S. Complex phenotype of mice lacking occludin, a component of tight junction strands. Mol Biol Cell. Dec;11(12):4131-4142.(2000)
Nose M, Terada M, Nishihara M, Kamogawa J, Miyazaki T, Qu W-M, Mori S, Nakatsuru S. Genome analysis of collagen disease in MRL/lpr mice: Polygenic inheritance resulting in the complex pathological manifestations. Int J Cardiol. Aug 31;75(SUPPL 1):S53-61; discussion S63.(2000)
Mimori-Kiyosue Y, Shiina N, Tsukita S. The dynamic behavior of the APC-binding protein EB1 on the distal ends of microtubules. Curr Biol. Jul 1;10(14):865-868.(2000)
Qu W-M, Miyazaki T, Terada M, Lu L-M, Nishihara M, Yamada A, Mori S, Nakamura Y, Ogasawara H, Yazawa C, Nakatsuru S, Nose M. Genetic dissection of vasculitis in MRL/lpr lupus mice: A novel susceptibility locus involving the CD72(c) allele. Eur J Immunol. Jul;30(7):2027-2037.(2000)
Ono Y, Nakanishi H, Nishimura M, Kakizaki M, Takahashi K, Miyahara M, Satoh-Horikawa K, Mandai K, Takai Y. Two actions of frabin: Direct activation of Cdc42 and indirect activation of Rac. Oncogene. Jun 22;19(27):3050-3058.(2000)
Yoneda O, Imai T, Goda S, Inoue H, Yamauchi A, Okazaki T, Imai H, Yoshie O, Bloom E.T, Domae N, Umehara H. Fractalkine-mediated endothelial cell injury by NK cells. J Immunol. Apr 15;164(8):4055-4062.(2000)
Imai T. Chemokine expression in insect cells. Methods Mol Biol. 138(23-32):(2000)
Imai T. Cloning of novel chemokines using a signal sequence trap method. Methods Mol Biol. 138(11-21):(2000)
Goda S, Imai T, Yoshie O, Yoneda O, Inoue H, Nagano Y, Okazaki T, Imai H, Bloom E.T, Domae N, Umehara H. CX3C-chemokine, fractalkine-enhanced adhesion of THP-1 cells to endothelial cells through integrin-dependent and -independent mechanisms. J Immunol. 164(8):4313-4320.(2000)
1999
Kamogawa J, Terada M, Nishihara M, Mizuki S, Mori S, Nakatsuru S, Nakamura Y, Nose M. Susceptibility loci to autoimmune arthritis in MRL/lpr mice. Nihon Rinsho Men'eki Gakkai kaishi = Japanese journal of clinical immunology. Dec;22(6):487-490.(1999)
Nishihara M, Terada M, Kamogawa J, Ohashi Y, Mori S, Nakatsuru S, Nakamura Y, Nose M. Genetic basis of autoimmune sialadenitis in MRL/lpr lupus-prone mice: Additive and hierarchical properties of polygenic inheritance. Arthritis Rheum. Dec;42(12):2616-2623.(1999)
Kubo A, Sasaki H, Yuba-Kubo A, Tsukita S, Shiina N. Centriolar satellites: Molecular characterization, ATP-dependent movement toward centrioles and possible involvement in ciliogenesis. J Cell Biol. Nov 29;147(5):969-979.(1999)
Hiiragi T, Sasaki H, Nagafuchi A, Sabe H, Shen S.C, Matsuki M, Yamanishi K, Tsukita S. Transglutaminase type 1 and its cross-linking activity are concentrated at adherens junctions in simple epithelial cells. J Biol Chem. Nov 26;274(48):34148-34254.(1999)
Furuse M, Sasaki H, Tsukita S. Manner of interaction of heterogeneous claudin species within and between tight junction strands. J Cell Biol. Nov 15;147(4):891-903.(1999)
Nakatsuru S, Terada M, Nishihara M, Kamogawa J, Miyazaki T, Qu W-M, Morimoto K, Yazawa C, Ogasawara H, Abe Y, Fukui K, Ichien G, Ito MR, Mori S, Nakamura Y, Nose M. Genetic dissection of the complex pathological manifestations of collagen disease in MRL/lpr mice. Pathol Int. Nov;49(11):974-982.(1999)
Morita K, Sasaki H, Furuse M, Tsukita S. Endothelial claudin: Claudin-5/TMVCF constitutes tight junction strands in endothelial cells. J Cell Biol. Oct 4;147(1):185-194.(1999)
Sonoda N, Furuse M, Sasaki H, Yonemura S, Katahira J, Horiguchi Y, Tsukita S. Clostridium perfringens enterotoxin fragment removes specific claudins from tight junction strands: Evidence for direct involvement of claudins in tight junction barrier. J Cell Biol. Oct 4;147(1):195-204.(1999)
Kubota K, Furuse M, Sasaki H, Sonoda N, Fujita K, Nagafuchi A, Tsukita S. Ca(2+)-independent cell-adhesion activity of claudins, a family of integral membrane proteins localized at tight junctions. Curr Biol. Aug 23;9(18):1035-1038.(1999)
Morita K, Sasaki H, Fujimoto K, Furuse M, Tsukita S. Claudin-11/OSP-based tight junctions of myelin sheaths in brain and Sertoli cells in testis. J Cell Biol. May 3;145(3):579-588.(1999)
Takai Y, Shimizu K, Ohtsuka T. The roles of cadherins and nectins in interneuronal synapse formation. Curr Opin Neurobiol.13(5):520-6.(2003)
Mimori-Kiyosue Y, Tsukita S. "Search-and-capture" of microtubules through plus-end-binding proteins (+TIPs). J Biochem.134(3):321-6.(2003)
Mimori-Kiyosue Y, Tsukita S. Where is APC going?. J Cell Biol.154(6):1105-9.(2001)
Nose M, Nishihara M, Kamogawa J, Terada M, Nakatsuru S. Genetic basis of autoimmune disease in MRL/lpr mice: dissection of the complex pathological manifestations and their susceptibility loci. Rev Immunogenet.2(1):154-64.(2000)
Nishimura M, Kuboi Y, Muramoto K, Kawano T, Imai T. Chemokines as novel therapeutic targets for inflammatory bowel disease. Ann N Y Acad Sci.1173:350-6.(2009)
Umehara H, Bloom E.T, Okazaki T, Nagano Y, Yoshie O, Imai T. Fractalkine in vascular biology: from basic research to clinical disease. Arterioscler Thromb Vasc Biol.24(1):34-40.(2004)
Umehara H, Bloom E, Okazaki T, Domae N, Imai T. Fractalkine and vascular injury. Trends in Immunology.22(11):602-7.(2001)
Umehara H, Imai T. Role of fractalkine in leukocyte adhesion and migration and in vascular injury. Drug News Perspect.14(8):460-4.(2001)
Yoshie O, Imai T, Nomiyama H. Chemokines in immunity. Adv Immunol.78:57-110.(2001)
