2015年5月16-19日、米国ワシントンDCにて開催されたDigestive Disease Week（DDW：米国消化器病週間）2015にて、池田わたる主幹研究員がポスター発表を行いました。

Advanced in vivo live imaging of vascular network of colon submucosa in IBD models using two-photon laser microscopy.
Wataru Ikeda¹, Akiko Hamaguchi¹, Yoshihisa Arita¹, Yoshikazu Kuboi², Kenzo Muramoto¹, and Toshio Imai¹
1. Concept Creation, KAN Research Institute, Inc., Kobe, Hyogo, Japan.
2. Product Creation, KAN-PCU, Eisai Co., Ltd., Tsukuba, Japan.

Background and aims

It has been reported that crawling/rolling monocytes in blood vessels play an important role in Inflammatory Bowel Disease (IBD). To monitor and evaluate these cells in IBD models, we established an advanced imaging system for immune cells, such as monocytes, in the mouse colon. Two-photon microscopy has revolutionized functional cellular imaging in tissue, but heartbeat and peristaltic movement of intestine interfere with imaging analysis of the colon. We studied the conditions for analysis with two-photon microscopy and developed a new device for live two-photon imaging of the colon.

続きはDDWオフィシャルサイト アーカイブにてご覧ください。
https://ddw.scientificposters.com/epsAbstractDDW.cfm?id=3

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