The World Health Organization (WHO) defines health as “a dynamic state of complete physical, mental, spiritual and social well-being and not merely the absence of disease or infirmity.” Rephrased from a largely biomedical perspective, this essentially refers to health as a state in which the body’s biological activities are taking place in well-balanced homeostasis.
Recent advances in the fundamental and medical sciences continue to achieve modernization through newer and ever more sophisticated research tools that consistently reveal how communications at the molecular and cellular levels are dynamically orchestrated to form the “vital homeostasis” basic to the definition of health as defined above. It is this high-resolution research that makes clear to us that any vital activity must depend on a mutual and compensatory biological circuit if it is to achieve vital stability. Although we as mankind have only just begun to uncover the tip of the iceberg of life, I believe that such research is a form of art due to its sheer precision and sophistication.
When we fall ill, it is our feeling that something is not right, or more precisely, those symptoms that manifest accordingly once our biological homeostasis is under threat. And while, of course, our endogenous compensatory circuit will kick in and try to fix the problem, we must remain aware that there are plenty of cases where this self-cure mechanism will not prove to be adequately effective for any number of reasons. This is where medicine can and sometimes should support us to restore our homeostasis though whatever its mechanism of action may be to modify the compensatory biological circuit.
At KAN Research Institute then, it is our mission to create new drugs to this end. Every time a patient overcomes their illness is a cause for celebration, with cheers and smiles all around not only for the patients themselves but their families and loved ones as well. In this light, when I am asked why we choose to conduct drug discovery research, my answer is that we want to provide them support, that means to return smiles to the global community. We believe that what we can offer them should put them on track to complete physical, mental, spiritual and social well-being—to ensure the health of our fellow man. Such is the dedication with which we whole-heartedly apply ourselves to the field of drug discovery so as to make a sincere and worthwhile contribution to human society.
Tetsu KAWANO, M.D., Ph.D.
Member of the Board, Chief Clinical Science Officer